Proton Pump Inhibitors Including Rabeprazole and Pantoprazole by Chiral HPLC (TN-1102)

Abstract:

This technical note demonstrates the successful separation of protein pump inhibitors (PPI) Omeprazole, Lansoprazole, Rabeprazole, and Pantoprazole using Lux polysaccharide-based columns. These chiral separations indicate the potential to prepare enantiomerically pure forms of racemic active ingredients Pantoprazole (Protonix) and Rabeprazole (AcipHex) using chiral chromatography.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Lux Axia

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